[tt] Next Big Future - 3 new articles
Eugen Leitl
<eugen at leitl.org> on
Fri Jul 4 10:29:37 UTC 2008
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Date: Fri, 04 Jul 2008 02:16:40 -0400
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Subject: Next Big Future - 3 new articles
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"[2]Next Big Future" - 3 new articles
1. [3]Artificial DNA Made Exclusively of Nonnatural bases made in
Japan
2. [4]Carnival of Space Week 61
3. [5]Lester Brown Plan B is mathematically and logistically flawed
4. [6]More Recent Articles
5. [7]Search Next Big Future
[8]Artificial DNA Made Exclusively of Nonnatural bases made in Japan
Chemical structures and synthesis of artificial DNA. (a) Chemical
structures of two types of natural and nonnatural base pairs. (b)
Synthetic strategy for the artificial DNA
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[15]Japan makes artificial DNA H/T [16]nanowerk and [17]Alfin
[18]This is separate from the GNA that was created glycerol nucleic
acid (GNA, --a synthetic analog of DNA). It was made by Biodesign
Institute scientist John Chaput and his research team.
[19]It is also different from the two new base letters that were added
to regular DNA
To those who don't believe in a Technological Singularity - really ?
behind schedule ? no progress ? There just had to be a specification
of which artificial DNA breakthrough is being discussed from
announcements made this year.
[20]Artificial DNA Made Exclusively of Nonnatural C-Nucleosides with
Four Types of Nonnatural Bases
A new class of DNA-like oligomers made exclusively of nonnatural,
stable C-nucleosides. The nucleosides comprise four types of
nonnatural bases attached to a deoxyribose through an acetylene bond
with the b-configuration. The artificial DNA forms right-handed
duplexes and triplexes with the complementary artificial DNA. The
hybridization occurs spontaneously and sequence-selectively, and the
resulting duplexes have thermal stabilities very close to those of
natural duplexes. The artificial DNA might be applied to a future
extracellular genetic system with information storage and amplifiable
abilities.
Artificial DNA made exclusively of nonnatural nucleosides with four
types of nonnatural bases represents a new class of DNA-like synthetic
oligomers. The iG*/iC*-rich artificial DNA forms right-handed duplexes
with the complementary artificial DNA in a sequence-specific manner
with antiparallel orientation. The thermal stabilities and
thermodynamic parameters of the artificial duplexes are very close to
those of the natural duplexes in spite of differences in their
geometries and hydrogen-bonding patterns. On the other hand, the
artificial homooligomeric DNAs consisted only of A* and T* were found
to exclusively form triplexes. By means of the synthetic feasibility
of the artificial nucleoside unit, a variety of candidates for
nonnatural bases can be incorporated into the artificial DNA.
Therefore, the present molecular framework has a potential for storing
genetic information and for application to enzymatic replication
directed toward engineered genetics. Furthermore, the artificial DNA
may be a superior building scaffold for constructing nanostructures of
materials interest because of the stable C-nucleosides against
ubiquitous naturally occurring enzymes such as DNase.
FURTHER READING
[21]Supporting information on the procedures used for the artificial
DNA
[22]Further analysis from Ars Technica
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[40]Carnival of Space Week 61
[41]Carnival of Space week 61 is up at Mangsbatpage
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[48]This site contributed the article on hypersonic technology of the
Blackswift and other hypersonic programs
[49]Centauri Dreams look at the NanoSail-D: Solar Sail Deployment Plan
[50]Colony worlds look at solar steam to power martian cities
[51]21st century waves looks at 10 reasons why China is good for space
Check out the Carnival for a lot more.
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[69]Lester Brown Plan B is mathematically and logistically flawed
[70]Lester Brown is pushing an Earth Policy Institute plan for
replacing all coal, oil and most natural gas by 2020 Their
calculations for energy are flawed. It appears that they ignore
capacity factor. They also do not look at pricing or consider the
build up of factories and supply chain. Although I guess some of that
comes from an assumption of taking over (mobilizing) existing
automotive factories and converting them to building wind turbines.
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Plan B includes a cost of $4.5 trillion for the wind turbines alone.
This does not count the production of new factories and does not count
the build out of grid. It also does not address intermittent nature of
wind abd solar power. The supply chain build up is the bigger cost and
strain. Also, taking the necessary steel and concrete allocation.
Also, the biomass increase will still contribute to air pollution.
3000GW of wind in Plan B but wind has only 20-40% capacity factor. The
european avg is 25% load factor over the course of a year (European
average). US average is 30%. The US wind capacity produced 31 billion
kWh per year from 16.8GW)2007. American wind farms will generate an
estimated 48TWh from 24GW. So 3000GW would produce 5500 TWh.
UPDATE:
[77]Spreadsheets for Plan B indicate that there is a proper units
view:
It also indicates that while capacity factor is considered for overall
power. The intermittent nature of solar and wind power is not. Plan B
also focuses on electricity generation and while the initial charts
they use look at the total energy picture they will still have a lot
of oil usage for transportation and coal and oil usage for industrial
purposes. So the graph which shows no oil and coal usage is only
addressing electricity and not transportation and industrial energy
usage.
=========
Nuclear already generates 2600 TWh. [78]The base reference case for
the EIA International energy outloook 2008 is for an increase in
nuclear power to 3290 TWh in 2020 (no mobilization just existing
trends). 690 more TWh with no mobilization. The Lester Brown turn
there nose up at what people are already going to build with a
dismissive nuclear costs too much according to Amory Lovins, when the
plan is for upwards of $10 trillion in extra spending.
Spend a few billion on assisting and accelerating the development and
$500 billion for deployment of the MIT annular fuel system for 50%
power uprates to existing reactors. This would allow for 1600 more TWh
to the reactors that exist now and are planned to be built anyway. So
less than 10% of the spending to get 41% of what the wind energy
turbine build is targeting.
$2 trillion per year in energy infrastructure spending is already the
default projection for 2015.
In the IEO2008 reference case, the world's installed nuclear capacity
grows from 374 gigawatts in 2005 to 498 gigawatts in 2030. The IEO2008
projection for nuclear electricity generation in 2025 is 31 percent
higher than the projection published in IEO2003 only 5 years ago.
They rely heavily on efficiency gains from replacing cars to plug in
hybrids and new public transportation and changing out all appliances
and increasing industrial efficiency by upgrading to the most
efficient equipment.
This still leaves 300+ exajoules of coal, oil and natural gas. The
6000GW of renewables that they propose does not even replace the
electricity generation because of the reduced capacity factors.
They need to re-examine the calculations, the supply chain, the costs,
training of people to build and install, and existing trends that
would help with their goal of greenhouse gas reduction. They need to
consider how the biomass is increased to minimize environmental
impact. They do not just purposefully ignore political reality but
they ignore economics, business and engineering reality as well. There
charts hop from the overall energy picture to the electricity only
generation picture without clarifying what is being done at the
overall level.
A far better plan is the one presented by [79]McKinsey consulting for
offsetting climate change
[80]This site also offers a better energy plan
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----- End forwarded message -----
--
Eugen* Leitl <a href="http://leitl.org">leitl</a> http://leitl.org
______________________________________________________________
ICBM: 48.07100, 11.36820 http://www.ativel.com http://postbiota.org
8B29F6BE: 099D 78BA 2FD3 B014 B08A 7779 75B0 2443 8B29 F6BE
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