[tt] Next Big Future - 4 new articles
Eugen Leitl
<eugen at leitl.org> on
Tue Aug 19 16:12:14 UTC 2008
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Date: Thu, 31 Jul 2008 02:42:18 -0400
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Subject: Next Big Future - 4 new articles
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"[2]Next Big Future" - 4 new articles
1. [3]Hybrid plane with double Prius fuel efficiency.
2. [4]More Performance and cognitive enhancement
3. [5]Powering exoskeletons and other vehicles: Revolutionary
electric and fuel engines
4. [6]Preventing flu deaths
5. [7]More Recent Articles
6. [8]Search Next Big Future
[9]Hybrid plane with double Prius fuel efficiency.
[10]Mark D Moore of NASA had a presentation at the Electric aircraft
conference and described a hybrid plane that could achieve 720 mile
range and 100mpg with a speed of 80 knots (92.2 mph)
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The plane could fly from San Francisco, CA to Salt Lake City, Utah in
less than 8 hours (using 8 gallons of gas) or from San Francisco to
Los Angeles in less 4 hours (using 4 gallons of gas).
The proposal is to slightly modify a newly introduced electric
sailplane by having several small electric engines for more safety and
to add a compact combustion engine for more range.
[17]The electric sailplanes and motorized gliders were discussed on
this site as 438 mpg equivalent super-commuter planes with 100 mile
range.
Electric planes are flying now. The Pipestrel electric glider plane
exists now. The lightweight gas engines exist now.
The [18]Pipestrel Taurus Electro, motorized electric glider plane,
flying in the air. [19]More photos of the Pipestrel Electro are here
The Pipestrel Electro will soon have a better continuous operation
electric engine.
[20]Lightweight gas engines are listed here.
The engine for the Raytheon [21]Killer Bee UAV only weighs 16 lbs and
can get up to 25HP.
The Revetec X4V2 is 105 kg and gets up to 87HP.
[22]RadMax rotary engine is 42 lbs and 40 HP.
Integrating working engines with working electric planes. Iterate
designs and build to perfect but the engineering is very close to
creating working prototypes. It will then be a matter of scaling up
production.
There are many experimental electric plane designs
All electric planes will get better range with expected improved
technology
FURTHER READING
[23]The small engines suitable for these light planes are also ideal
for powering the DARPA exoskeleton, which would make real life iron
men. Strength is boosted ten times.
[24]CNET had coverage of the Pipestrel electro airplane
The glider weighs little more than 700 pounds and costs $133,000.
Richard Jones, a technical fellow at Boeing Phantom Works. The
research group is designing a plane-car hybrid to travel up to 300
miles at a time. Jones believes that by 2030, precision navigation
systems could make it easier to pilot a compact plane than to drive a
car.
Engineer Greg Stevenson displayed a two-cycle diesel engine that
weighs 18 pounds and can run on biofuels.
[25]The Speculist has a take on making the electric/hybrid flying
planes convert into cars by having the wing section detach. The
electric/hybrid car would be like the lightweight [26]Aptera three
wheel car.
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[44]More Performance and cognitive enhancement
[45]Popular Science looks at Juicing 3.0
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Better nootropic cognitive enhancers coming
Modafinil is but one of a dozen or so "neural enhancers" currently
available in pharmacies that scientists say could enhance athletic
performance. Popping FDA-approved Parkinson's meds and antidepressants
might not seem like cheating, but studies suggest that a positive
mental attitude improves mental focus, contributing to superior
performance. Extra serotonin may foster a more positive mood, while
both dopamine and norepinephrine seem to enhance motor control and
muscle reaction time.
"Within the next few years, we'll see the second generation of these
drugs," says Mark Gordon, an endocrinologist in Los Angeles. "Like all
second-generation drugs, they will be stronger, longer-lasting, and
have fewer side effects." The pharmaceutical industry makes a fortune
on these drugs, so nearly every major company has a brain booster or
two in the works.
Myostatin Update
In lab tests, two injections of one mysostatin blocker produced a
permanent 50 percent muscle gain in mice. "Just about every major
pharmaceutical company is developing a myostatin-blocking drug to
treat muscle-wasting diseases like muscular dystrophy," Lee says.
Because these medicines will use traditional antibody-based
drug-delivery methods, a myostatin inhibitor could be on the market
in five years.
Gene Doping
"Developing techniques that really work has been much harder than
people first thought," says Theodore Friedmann, director of the
Human Gene Therapy Program at the University of California at San
Diego and a consultant for the World Anti-Doping Agency (WADA).
There have been a few successes with gene therapy--in 2000,
scientists "cured" severe combined-immune-deficiency syndrome in
nine infants. It may take five years to work out issues for
reliable enhancement.
Stem cell therapy and Engineered Stem cells
The potential uses of stem-cell therapy seem endless: from treating
cancer and neurological diseases, to increasing muscle mass and bone
density in the weak, to cultivating new organs in petri dishes.
"We can already make adult stem cells form muscle," says Chris Evans,
a professor of orthopedic surgery at Harvard Medical School. "But how
to deliver stem cells to the appropriate muscle, and how to get that
muscle to integrate these newcomers and gain additional function,
remains a mystery." Scientists expect this barrier to fall in a
decade.
Similarly stem cells can be made to form brain cells.
Getting into the Zone
Athletes get the "in-the-zone" feeling where they have the sense
that they can accomplish anything. When Boston Celtic Larry Bird
talked about the game seeming to actually slow down during crunch
time, helping him to read defenses more clearly and feel more
fleet-footed, he was probably experiencing a natural dopamine high.
Dopamine increases muscle-reaction speed and alters the perception
of time. But these flow states, as they're known among
psychologists, are probably triggered by a surge of several
mindscrambling, euphoria-inducing, reflex-quickening
neurochemicals, such as norepinephrine and serotonin.
In 2004, neuroscientist Arne Dietrich, then at the Georgia
Institute of Technology, identified anandamine--the body's version
of THC, the psychoactive chemical in marijuana--as the chemical
most likely responsible for flow states. This theory received a
boost this spring, when scientists at the University of Bonn in
Germany found elevated levels of endorphins in the brains of test
subjects. These molecules are too big to penetrate the blood-brain
barrier on their own, so the current thinking is that anandamine
ferries them in and that it's the endorphins that provide the
actual high. Still, most scientists think there are other
neurochemicals in play, and figuring out the exact combination may
take years.
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[69]Powering exoskeletons and other vehicles: Revolutionary electric and
fuel engines
The highest power to weight ratio electric or combustion engines could
be used to power the Sarcos exoskeleton [as well as enable radically
more efficient planes, cars, motorcycles and scooters].
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[76]The Sarcos exoskeleton just needs a good powersource and engine to
power the hydraulics for it to enhance the strength and endurance of
someone who wears it by ten times
[77]It should be possible for someone with the untethered Sarcos
exoskeleton to carry and use a minigun A M134 7.62 minigun weighs 190
lbs (60 pounds for the gun and 130 lbs for 1500 rounds of ammo)
The gun used in Terminator 2, Matrix (mounted on helicopter) and other
movies. In real life used in Vietnam for firing out of helicopters.
[78]The XM312 50 caliber gun could also be carried and used by one
soldier in exoskeleton armor It delivers lethal and suppressive fire
out to 2,000 meters.
New electric and combustion engines could be up to the task. It may be
necessary to make half size versions of these engines to reduce the
overall weight. The person wearing the exoskeleton can carry 100-200kg
without tiring so having 60-100kg of weight for the power supply is
doable.
The electric engine could be recharged with a solar cell tent or
generators at a base camp. the gas engine could get refueled from
Humvees or MRAPs or other vehicles.
Besides the weigh of engine the batteries of fuel weight needs to be
considered.
A 13.2 kg, 30KW (40HP) electric engine made by Pipestrel
[79]This electric engine is being used to make hyperfuel efficient
motorized glider planes
[80]Revetec,a small Australia company, has created an engine that is
50% smaller, 50% lighter, has 50% lower emissions and is cheaper to
manufacture than a conventional internal combustion engine of the same
horsepower. It doubles the fuel economy.
[81]The X4v2 petrol engine achieved a repeatable Brake Specific Fuel
Consumption (BSFC) figure of 212g/kW-h (38.6% engine efficiency) with
a best figure of 207g/kW-h (39.5%) at our requested target test of
2,000rpm with a BMEP load of 450kpa (approximately 75% load) and an
air/fuel ratio of 15.2:1 using 98 RON petrol and a 10:1 compression
ratio. We also achieved a BSFC figure under the same rev and load
conditions using an air/fuel ratio of 14.5:1 of 238g/kW-h (34.4%).
[82]At 2000 rpm the engine generated 18kw and at higher rpm up to 65kw
[24-87HP] The full load torque ranged from 132.9 to 176.1 Nm between
1500 and 3500 rpm.
[83]The production engine weight for the X4V2 is 105 kg.
The engine for the killer Bee UAV only weighs 16 lbs and can get up to
25HP. Needs to be built with higher endurance as it needs overhaul
every 300 hours.
FURTHER READING
[84]Power to weight ratio
[85]Projected advances in engine and power storage to 2020
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[103]Preventing flu deaths
[104]Researchers from Imperial College in London, England, isolated
the receptor in the lungs that triggers the immune overreaction to
flu.
With the receptor identified, a therapy can be developed that will
bind to the receptor, preventing the deadly immune response. Also, by
targeting a receptor in humans rather than a particular strain of flu,
therapies developed to exploit this discovery would work regardless of
the rapid mutations that beguile flu vaccine producers every year.
[105]The flu kills 250,000 to 500,000 people in an average year with
epidemics reaching 1 to 2 million deaths (other than the spanish flu
which was more severe
This discovery could lead to treatments which turn off the
inflammation in the lungs caused by influenza and other infections,
according to a study published today in the [106]journal Nature
Immunology. The virus is often cleared from the body by the time
symptoms appear and yet symptoms can last for many days, because the
immune system continues to fight the damaged lung. The immune system
is essential for clearing the virus, but it can damage the body when
it overreacts if it is not quickly contained.
The immune overreaction accounts for the high percentage of young,
healthy people who died in the vicious 1918 flu pandemic. While the
flu usually kills the very young or the sickly and old, the pandemic
flu provoked healthy people's stronger immune systems to react even
more profoundly than usual, exacerbating the symptoms and ultimately
causing between 50 and 100 million deaths world wide. These figures
from the past make the new discovery that much more important, as new
therapies based on this research could prevent a future H5N1 bird flu
pandemic from turning into a repeat of the 1918 Spanish flu.
In the new study, the researchers gave mice infected with influenza a
mimic of CD200, or an antibody to stimulate CD200R, to see if these
would enable CD200R to bring the immune system under control and
reduce inflammation.
The mice that received treatment had less weight loss than control
mice and less inflammation in their airways and lung tissue. The
influenza virus was still cleared from the lungs within seven days and
so this strategy did not appear to affect the immune system's ability
to fight the virus itself.
The researchers hope that in the event of a flu pandemic, such as a
pandemic of H5N1 avian flu that had mutated to be transmissible
between humans, the new treatment would add to the current arsenal of
anti-viral medications and vaccines. One key advantage of this type of
therapy is that it would be effective even if the flu virus mutated,
because it targets the body's overreaction to the virus rather than
the virus itself.
In addition to the possible applications for treating influenza, the
researchers also hope their findings could lead to new treatments for
other conditions where excessive immunity can be a problem, including
other infectious diseases, autoimmune diseases and allergy.
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More Recent Articles
* [124]The future of fast long range commuting: 438 mpg Commuter UAV
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Alzheimers
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----- End forwarded message -----
--
Eugen* Leitl <a href="http://leitl.org">leitl</a> http://leitl.org
______________________________________________________________
ICBM: 48.07100, 11.36820 http://www.ativel.com http://postbiota.org
8B29F6BE: 099D 78BA 2FD3 B014 B08A 7779 75B0 2443 8B29 F6BE
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