[tt] advanced nanotechnology - 9 new articles
Eugen Leitl
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Sun Sep 23 10:55:29 UTC 2007
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Subject: advanced nanotechnology - 9 new articles
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"[2]advanced nanotechnology" - 9 new articles
1. [3]Some clarification of my CRN presentation
2. [4]Simple and cheap way to make carbon nanotube based computer
chips
3. [5]Update on new cancer treatment reported at SENS3
4. [6]New Lung cancer test for 99% effective early detection
5. [7]New Cancer treatment effective in providing lifetime immunity
to cancer in mice could be treating humans in 2 years with simple
blood product transfusion [del.icio.us]
6. [8]Carnegie Mellon Building Robot for Lunar Prospecting
7. [9]Di-positronium > Gamma Ray Lasers > Laser ignition nuclear
fusion
8. [10]Lasers for purifying blood and detecting cancer
9. [11]Middle east war possibilities
10. [12]More Recent Articles
11. [13]Search advanced nanotechnology
[14]Some clarification of my CRN presentation
[15]The Register discusses the CRN conference, where I was one of the
presenters
I need to correct some misunderstanding from a lack of clarity in one
of my presentation slides.
Register person had stated I was saying molecular manufacturing would
happen in 2015. [16]My prediction for a nanofactory level of
capability in molecular manufacturing is 2015-2023 If a lot of bad
choices are made and the development work turns out to be surprisingly
difficult then 2024-2030 is very possible. However, the almost
molecular manufacturing capability will be getting better and better
so I am not clear what would be preventing someone from bootstrapping
to the full capability for the longer time frame.
One of my presentation slides gave the impression that societies
energy problems would persist for decades after the arrival of full
blown molecular manufacturing.
Energy, space and infrastructure problems which are some of the will
take the longest to fix now will potentially be very easy after
molecular manufacturing arrives. The expection is whatever ongoing bad
choices we are making as a society can continue to prevent problems
from being solved.
This is currently the case with many of todays problems. The technical
capability has been available to solve energy and space access,
however the collective choices made in different parts of society have
prevented us from getting over the hurdles needed to implement
solutions.
For example, corruption and violence in Africa prevents those
countries from experiencing an economic boom similar to China and
Vietnam and other countries.
The Africa-lite levels of corruption and violence in countries like
the United States and Europe and China could prevent the full
potential of molecular manufacturing from being realized. Just as
current bad funding choices are delaying the development of molecular
manufacturing.
The technology can enable the fixes. It is we who could continue to
screw it up as we have up to this point under-utilizing possible
solutions.
Technology, even powerful technology such as molecular manufacturing
is not beyond the power of bad choices to screw it up. I am somewhat
less concerned about the bad choices that could lead to extinction
(although those are a concern) than I am about massive civilization
underperformance. Massive civilization underperformance has been a
persistent problem throughout history, which I would like to see
reduced. Also, if it was reduced civilization would be more robust and
better able to handle and prevent extinction risks as well.
We marvel at the [17]50 trillion world GDP (70 trillion a purchasing
power parity basis). However, bad governance and bad choices
throughout even relatively recent history have caused the
underperformance of the world economy. China did not have to be a
basketcase economy from 1900 to 1975 (and even from 1500-1900). India
also could started its climb out of poverty decades earlier. The
people in India who cling to a stifling bureaucracy and the systems
which encourage that behavior could have been removed and reduced
sooner. The world economy could be two to three times bigger than it
is now.
The United States could have been building nuclear plants for power
without the 30 year gap. 400 more nuclear plants would have meant
having the 80% French level of nuclear electricity generation. $300
billion/year in pollution and health costs could be saved. The reduced
medical costs would make medicare more solvent and have reduced taxes
and better balanced budgets. There would also have been fewer wars for
oil.
Even the measurement of size of the world economy does not address how
much useless busy work or destructive work there is. Using 40% of the
railway and 10% of frieght to move 1 billion tons in the USA of coal
(6-7 billion tons worldwide) generates a lot of GDP activity. However,
this is including a lot of destructive and unnecessary activity as a
positive.
The lost opportunity cost from bad research and development choices
and from research and development funding system inefficiencies are
very high. [18]Alan Shalleck discusses how the first few years and
billions of dollars in nanotechnology budgets have gone to
establishing nanotechnology laboratory facilities, outfitting these
laboratories with nanotech capable instrumentation, finding and
recruiting nonscientists who were fascinated by the nanotechnology
opportunity and funding basic nanoscience research.
There was no expectation of any nanotechnology product. There was no
goal or plan by design. [19]No stated goal means no standard of
achievement to be held accountable No stated goal or objective meant
that there could no specific genetically modified food controversy,
because there would not be nothing made and no stated plans for
production there could be no controversial impact. This is a systemic
wasteful and underperforming behavior. My main hope and expectation is
that increasing true competition from other countries will force more
productive behavior and bolder efforts and plans.
I think there are some trends that will force a higher standard of
competence and rational evidence based thinking. The [20]flattening of
the world and increasing global competition will mean less places for
incompetence to persist and dominate. Open hypercompetition lets the
winner win faster and prevents the idiots from letting screw ups
persist.
The shape of the future will be decided by an ongoing battle between
incompetence and selfish corrupt decision making versus
super-technology and efficient and rapid assessment and analysis with
evidence based choices.
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[34]Simple and cheap way to make carbon nanotube based computer chips
[35]Scientists in Israel are reporting the first simple and
inexpensive method for building the large-scale networks of
single-walled carbon nanotubes (SWCNT) needed for using these
microscopic wisps in a future generation of faster, smaller, and more
powerful computers and portable electronic devices.
[070917112542.jpg]
Photo and illustration (inset) of carbon nanotube circuits. (Credit:
Courtesy of Ze'ev Abrams and Yael Hanein, Tel-Aviv University, Israel)
The study describes a method to manufacture and assemble large
arrays of SWCNTs into an integrated circuit format. It can be used
on a variety of surfaces and produced on an industrial scale. The
process involves creating networks of nanotubes suspended between
silicon pillars, which are then transferred onto other surfaces by
direct stamping, the researchers say.
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chips'
[49]Update on new cancer treatment reported at SENS3
[50]From the Telegraph, cancer sufferers could be cured with
injections of immune cells from other people within two years. Dr
Zheng Cui, of the Wake Forest University School of Medicine, has shown
in laboratory experiments that immune cells from some people can be
almost 50 times more effective in fighting cancer than in others. The
treatment is called "GIFT" (Granulocyte InFusion Therapy).
[51]The Fight Aging blog indicates that Dr Cui's work is important,
and an impressive technology demonstration, but still pre-trial and
one of dozens of just as effective demonstrated means to kill cancer.
I think that because this treatment is so simple and similar to other
methods that the delay until it is shown to work and optimized and
until it is used should be far shorter than some other methods. FDA
approval of some drugs is as long as 17 years.
I think one of the best ways to provide this immune system boost is
before there is any cancer. Just as there is 80% survival for stage 0
cancer versus 2% survival for stage 5, getting the GIFT boost similar
to a vaccination could prevent cancer from getting a toe hold. Other
treatments like chemo therapy kill even higher percentages of cancer
cells but are applied later in the disease progression and have side
effects. If the immune system boost can applied without
causing[52]graft versus host disease, then this could be a prevention
for cancer. [53]Wikipedia discusses transfusion associated graft
versus host disease
[54]This is a follow up to my article a few days ago on this treatment
which was announced at the SENS3 conference
[55]del.icio.us
Dr Cui is confident patients could benefit from the technique
quickly because the technology used to extract granulocytes is the
same as that already used by hospitals to obtain other blood
components such as plasma or platelets.
Last year Dr Cui caused shockwaves in the cancer research community
when he identified granulocytes as the cells responsible for the
mouse cancer immunity - because they are among those which act
automatically.
Prof Gribben said: "This is surprising because it goes against how
we thought immune system works against cancer. It makes us think
again about our preconceived notions."
Prof Cui injected granulocytes from immune mice into ordinary mice,
and found it was possible to give them protection from cancer.
Even more excitingly he found the transfusions caused existing
cancers to go into remission and to clear them completely within
weeks.
A single dose of the cells appeared to give many of the mice
resistance to cancer for the rest of their lives.
Prof Gribben warned the US researchers would have to be careful to
avoid other immune system cells from the donor proliferating in the
patient's body.
He added: "If they're using live cells there is a theoretical risk
of graft-versus-host disease, which can prove fatal."
Dr Cui said he is working on ways to minimise this risk
[cancergraphic.gif]
How the cancer treatment would work
FURTHER READING:
[56]New Scientist has a video of granulocytes killing cervical cancer
cells
[57]The abstract of Dr Cui's SENS 3 conference presentation
While most of the research attention has been focused on the
question, why cancer occurs in about 25% of humans, a less
frequently asked question has been why the other 75% of humans do
not get cancer. Cigarette-smoking is a highly reliable way for
humans to expose themselves to known carcinogens, causing a
100-fold increase of lung cancer rates from 0.08% in the general
population to 8% in smokers. Why do the other 92% of smokers not
get cancer? It has long been speculated that there is a cancer
surveillance system in humans. There must be something that
protects healthy humans from getting cancer, even after repeated
exposures to carcinogens... Based on these findings and the ability
to screen for cancer-resistant humans as allogenic white cell
donors, we proposed a new cancer treatment strategy, termed "GIFT"
(Granulocyte InFusion Therapy), that will soon enter phase II
clinical trials
[58]Dr Cui's homepage
[rsg_zcmwmouse.jpg]
Dr Cui and his cancer resistant mice
[59]99% effective early detection of lung cancer could also boost
survival rates. Early detection survival rates 80% vs late detection
at 2%
[60]Futurepundit also speculates on this cancer treatment
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[74]New Lung cancer test for 99% effective early detection
[75]esearchers at a Gaithersburg, MD, pharmaceutical company say they
have found that 99 percent of patients with all stages of lung cancer
have detectable levels of a particular protein in their blood that
healthy individuals do not. The company, Panacea Pharmaceuticals, is
reporting encouraging preliminary results for its test for the protein
this week at a conference of the American Association for Cancer
Research.
[76]Lung cancer survival rates are as high as 80% for stage 0 lung
cancer If all lung cancer was detected early then survival rates would
be far higher.
Stage 0 Lung Cancer
The lung cancer is localized
Five-Year Survival Rate = 70 - 80%
Stage I Lung Cancer
The lung cancer is confined to the lungs and surrounded by normal
tissue.
Five-Year Survival Rate = 50%
Stage II Lung Cancer
The lung cancer has spread to nearby lymph nodes.
Five-Year Survival Rate = 30%
Stage III Lung Cancer
The lung cancer has spread to the chest wall, diaphragm, or other
nearby organs or blood vessels.
Five-Year Survival Rate = 5 - 15%
Stage IV Lung Cancer
The lung cancer has spread to more distant sites in the body.
Five-Year Survival Rate = Less than 2%
RELATED NEWS
[77]Genetic screening for breast cancer is making breast cancer
testing faster and a lot cheaper
[78]Genetic tests for prostate cancer are also being developed.
Doctors hope that it will make diagnosis of the disease more accurate
and reduce the number of biopsies (removal of tissue samples) that are
obtained through painful procedures.
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[91]Rate 'New Lung cancer test for 99% effective early detection'
[92]New Cancer treatment effective in providing lifetime immunity to cancer
in mice could be treating humans in 2 years with simple blood product
transfusion [del.icio.us]
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[97]Rate 'New Cancer treatment effective in providing lifetime
immunity to cancer in mice could be treating humans in 2 years with
simple blood product transfusion [del.icio.us]'
[98]Carnegie Mellon Building Robot for Lunar Prospecting
[99]Researchers in the Robotics Institute of Carnegie Mellon
University's School of Computer Science are building a robotic
prospector for NASA that can creep over rocky slopes and then anchor
itself as a stable platform for drilling deep into extraterrestrial
soils.
[Press%20Release%20Photo.jpg]
Called "Scarab," this four-wheeled robot will never leave the Earth.
But it will demonstrate technologies that a lunar rover will need to
find concentrations of hydrogen, possibly water and other volatile
chemicals on the moon that could be mined to produce fuel, water and
air that are essential for supporting lunar outposts.
Scarab is equipped with a Canadian-made drill for obtaining
meter-long geological core samples and features a novel rocker-arm
suspension that enables the robot to plant its belly on the ground
for drilling operations.
To optimize efficiency, the robot must be as light as possible. But
to operate the coring drill, the vehicle also has to be massive
enough to apply sufficient downward pressure on the drill and
counter the torque of the rotating drill. Researchers estimate it
must weigh at least 250 kilograms, or about 550 pounds.
The suspension allows Scarab to make the most of its weight by
enabling it to lower its 5 1/2-foot-by-3-foot body to the ground
for drilling operations. "One of the design innovations was to put
the drill in the center of the robot," Wettergreen said, rather
than attaching it to an arm. "Scarab can apply its entire mass onto
the drill, so that everything is assisting the drilling operation."
Whittaker has announced that he is assembling a team to compete for
the Google Lunar X-Prize and its $20 million grand prize for
operating a privately funded robot on the moon by 2012. That effort
is separate and distinct from the NASA-funded Scarab project, which
is developing technologies that could be used on the moon but are
being tested on Earth.
I wish his team good luck on winning the X-prize. They would
definitely have a very capable rover. [100]I had posted my own outline
of how to win the Google XPrize
Winning is buying a rocket ride to orbit, earth orbit to lunar orbit
low energy transfer, lunar lander (several are available) and rover.
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[114]Di-positronium > Gamma Ray Lasers > Laser ignition nuclear fusion
[115]A US team has created thousands of Di-positronium molecules by
merging electrons with their antimatter equivalent: positrons. The
discovery, reported in the journal Nature, is a key step in the
creation of ultra-powerful lasers known as gamma-ray annihilation
lasers.
Gamma ray lasers would have a lot of uses. The progress with Bose
condensates and with positron traps has proceeding fairly quickly.
This could be a fairly rapid technological progression with a lot of
other new technological possibilities along the way. It also sounds
like it will be fairly compact and lightweight, which would be good
for any fusion propulsion system.
[070912154633.jpg]
The ultra-high vacuum target chamber, where the intense positron
pulse is implanted into the porous silica film. The magnet coils
carry a current of 1000 amps for a few hundred milliseconds to
generate the strong magnetic field needed to compress the positron
beam. (Credit: David Cassidy, UC-Riverside)
To make the molecules, Dr Cassidy and his team used a specially
designed trap to store millions of the positrons.
A burst of 20 million were then focused and blasted at a porous
silica "sponge".
"It's like having a trickle of water filling up a bath and then you
empty it out and you get a big flush," said Dr Cassidy.
As the positrons rushed into the voids they were able to capture
electrons to form atoms. Where atoms met, they formed molecules.
By measuring the gamma-rays that signalled their annihilation, the
team estimated that up to 100,000 of the molecules formed, albeit
for just a quarter of a nanosecond (billionth of a second).
Dr Cassidy believes that increasing the density of the positronium
in the silicon would create an exotic state of matter known as a
Bose-Einstein condensate (BEC).
"At even higher densities, one might expect the material to become
a regular, crystalline solid," wrote Professor Clifford Surko, of
the University of Californian, San Diego, in an accompanying
article.
Taking it one step further, scientists could use the spontaneous
annihilation of the BEC, and the subsequent outburst of gamma-rays,
to make a powerful laser.
He highlighted an experiment at the National Ignition Facility
(NIF) in the US where scientists envisage using 192 lasers to heat
a fuel target to try to kick-start nuclear fusion.
"Imagine doing that but you no longer need hundreds of lasers," he
said.
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[129]Lasers for purifying blood and detecting cancer
[130]Businessweek indicates that new short pulse lasers can also
shatter the outer membranes of viruses, which suggests they can be
used to purify donated blood. A father-son team of scientists--one a
laser expert at the University of Arizona, and the other an immunology
student at Johns Hopkins University--built one that emits pulses of
light at a frequency that kills viruses without harming normal cells.
Another new laser device could let doctors peer through the skin and
into the veins of patients' wrists to spot cancer cells in the blood.
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[144]Middle east war possibilities
[145]The International Herald Tribune discusses a Middle East
literally in flames from the Hindu Kush to the Mediterranean is by no
means a distant or unrealistic prospect.
On the face of it, neither country has anything to gain from war,
since neither can possibly prevail. Syria is too weak reconquer its
lost territory and Israel is too small to take and hold much more
of Syria.
Both, however, have more subtle objectives in view. Israel wants to
restore the prestige and deterrent credibility lost last year in
its ill-conceived invasion of Lebanon. Syria wants to sustain
pressure upon Israel via its Lebanese proxies with a view to
boosting its stature in the region and ultimately ending the
Israeli occupation of the Golan Heights.
The real issue is what Washington has to gain from another Middle
East war. The Bush administration has acknowledged that Israel
attacked Syrian last week, but has not given any indication that
the United States sought to prevent it, or discourage a repetition.
Finding out exactly what the United States is doing to forestall a
war between Israel and Syria would seem important.
[146]Washington Post on the Israeli bombing of Syria
Israel's decision to attack Syria on Sept. 6, bombing a suspected
nuclear site set up in apparent collaboration with North Korea,
came after Israel shared intelligence with President Bush this
summer indicating that North Korean nuclear personnel were in
Syria, U.S. government sources said.
The United States is believed to have provided Israel with some
corroboration of the original intelligence before Israel proceeded
with the raid, which hit the Syrian facility in the dead of night
to minimize possible casualties, the sources said.
Unlike its destruction of an Iraqi nuclear reactor in 1981, Israel
made no announcement of the recent raid and imposed strict
censorship on reporting by the Israeli media. Syria made only muted
protests, and Arab leaders have remained silent. As a result, a
daring and apparently successful attack to eliminate a potential
nuclear threat has been shrouded in mystery.
"There is no question it was a major raid. It was an extremely
important target," said Bruce Riedel, a former intelligence officer
at Brookings Institution's Saban Center for Middle East Policy. "It
came at a time the Israelis were very concerned about war with
Syria and wanted to dampen down the prospects of war. The decision
was taken despite their concerns it could produce a war. That
decision reflects how important this target was to Israeli military
planners."
[147]Washingpost Oped: Israel Attacks Syria and Everyone Wins
[148]The Times online tracks the possibility of war with Iran.
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More Recent Articles
* [162]Why government nanotech initiatives have no point
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value [del.icio.us]
* [164]Next generation of chinese leaders taking the world stage
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* [166]Canadian dollar and US dollar are at parity
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172. http://www.feedblitz.com/
173. http://www.feedblitz.com/
----- End forwarded message -----
--
Eugen* Leitl <a href="http://leitl.org">leitl</a> http://leitl.org
______________________________________________________________
ICBM: 48.07100, 11.36820 http://www.ativel.com http://postbiota.org
8B29F6BE: 099D 78BA 2FD3 B014 B08A 7779 75B0 2443 8B29 F6BE
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