[tt] advanced nanotechnology - 2 new articles

Eugen Leitl <eugen at leitl.org> on Sun Oct 21 13:03:29 UTC 2007

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Date: Sun, 21 Oct 2007 03:18:14 -0400
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Subject: advanced nanotechnology - 2 new articles
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"[2]advanced nanotechnology" - 2 new articles

    1. [3]Myostatin drugs possibly four times better muscle growth than
       steroids without the harmful side effects
    2. [4]Multi-wall carbon nanotubes increase light emission of polymer
       100 fold
    3. [5]More Recent Articles
    4. [6]Search advanced nanotechnology

[7]Myostatin drugs possibly four times better muscle growth than steroids
without the harmful side effects

   [8]The drug ACE-031 has been found to reproduce the enhanced muscle
   growth effect caused by certain genes. Genetic manipulation in mice
   can cause 4 times the muscle growth. The drug mimics the effect of
   gene therapy and appears to be a super-steroid without the harmful
   effects and is using a different process than steroids.
   [whippet_x220.jpg]
   The dog in the photo is supermuscular because of naturally occurring
   mutations that silence both versions of the myostatin gene. Called
   bully whippets, these dogs are rarely champion racers. However,
   animals with one mutated and one normal version of the gene are more
   muscular than typical animals and are among the breed's fastest
   racers. Credit: Stuart Isett, Polaris

     Mice given the new drug show a 30 to 60 percent increase in muscle
     mass, and mice with a version of muscular dystrophy show increased
     grip strength, a standard measure of rodent strength. Preliminary
     results from primate studies show that the animals on the drug bulk
     up at similar rates to those seen in rodents. "Before I became
     involved with Acceleron, if someone had told me you could increase
     muscle mass by up to 60 percent in a month, I never would have
     believed it," says CEO John Knopf.
     While it's not yet clear if similar rates will be seen in humans,
     high doses of anabolic steroids, which carry serious side effects,
     increase muscle mass by a maximum of 15 to 20 percent. And because
     myostatin is found only in muscle, knocking it out does not appear
     to have the adverse effects of broader-acting steroids.
     Says Evans, "I think these drugs, perhaps used in combo with
     exercise, might have great potential in reversing the trend toward
     increasing obesity and decreasing muscle mass."

   [9][advancednano?i=Vt8JfEA] [10][advancednano?i=L6Ehcya]
   [11][advancednano?i=0S7hi3a] [12][advancednano?i=XDvBroa]
   [13][advancednano?i=BjToEOa] [14][advancednano?i=HAJfi9A]
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[22]Multi-wall carbon nanotubes increase light emission of polymer 100 fold

   [23]Researchers at the Advanced Technology Institute of the University
   of Surrey, in collaboration with researchers from China and the USA,
   have demonstrated a 100-fold increase in the light emission from a
   nylon polymer sample, by incorporating multi-walled carbon nanotubes
   (MWCNT).

     Previously adding carbon nanotubes (CNT) reduces the light emission
     from the composite, due to quenching of charge carriers at the
     nanotubes, which are generally metallic in nature for multi-walled
     CNT. This quenching reduces the emission efficiency of the devices.
     This increase in light-emission only occurred when they acid
     treated the MWCNT prior to inclusion in the polymer. They propose
     that this increase is due to a novel energy transfer mechanism,
     from the acid-damaged surface of the MWCNT to the emitting sites in
     the polymer. In addition to the enhanced light-emission, the study
     also demonstrates that the MWCNT produced an improvement in the
     stability of the polymer to light-induced degradation.
     Dr. Simon Henley, one of the lead investigators, comments "These
     results show that carbon nanotubes have enormous potential as a
     versatile material in future optoelectronic devices, and raise the
     prospect of utilising MWCNTs to harvest solar radiation in organic
     solar cells, in addition to improving device stability. "
     Professor Ravi Silva, Director of the Advanced Technology Institute
     states: "The mere fact that now we can have a predictable
     organic-nanotube hybrid composite, with enhanced properties should
     open the door for many new applications. The enhancement in the
     luminescence properties bodes well a new generation of organic
     devices that could potentially reach commercially viable figures of
     merit for large scale production.

   [24][advancednano?i=SnIg1aA] [25][advancednano?i=XxCCMRa]
   [26][advancednano?i=Oo4Obea] [27][advancednano?i=WY7dpYa]
   [28][advancednano?i=dAlqJ2a] [29][advancednano?i=vg0T9HA]
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   [36]Rate 'Multi-wall carbon nanotubes increase light emission of
   polymer 100 fold'

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