[tt] advanced nanotechnology - 5 new articles

Eugen Leitl <eugen at leitl.org> on Tue Nov 20 09:04:16 UTC 2007

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"[2]advanced nanotechnology" - 5 new articles

    1. [3]Detecting chemical reactions in a single living cell for the
       first time
    2. [4]Help hookup.com, an army of volunteers
    3. [5]Interviewed by the speculist.com
    4. [6]Progress on Stronger Carbon-Nanotube Fibers
    5. [7]Personal DNA services for about $1000
    6. [8]More Recent Articles
    7. [9]Search advanced nanotechnology

[10]Detecting chemical reactions in a single living cell for the first time

   [11]Bioengineers at the University of California, Berkeley, have
   discovered a technique that for the first time enables the detection
   of biomolecules' dynamic reactions in a single living cell.
   They can determine in real time whether specific enzymes are activated
   or particular genes are expressed, all with unprecedented resolution
   within a single living cell. This could lead to a new era in molecular
   imaging with implications for cell-based drug discovery and biomedical
   diagnostics.
   The researchers tackled this challenge by improving upon conventional
   optical absorption spectroscopy, a technique by which light is passed
   through a solution of molecules to determine which wavelengths are
   absorbed. Cytochrome c, for instance, is a protein involved in cell
   metabolism and cell death that has several optical absorption peaks of
   around 550 nanometers.
   The researchers came up with a novel solution to this problem by
   coupling biomolecules, the protein cytochrome c in this study, with
   tiny particles of gold measuring 20-30 nanometers long. The electrons
   on the surface of metal particles such as gold and silver are known to
   oscillate at specific frequencies in response to light, a phenomenon
   known as plasmon resonance. The resonant frequencies of the gold
   nanoparticles are much easier to detect than the weak optical signals
   of cytochrome c, giving the researchers an easier target.
   Gold nanoparticles were chosen because they have a plasmon resonance
   wavelength ranging from 530 to 580 nanometers, corresponding to the
   absorption peak of cytochrome c.
   The researchers repeated the experiment matching the protein
   hemoglobin with silver nanoparticles and achieved similar results.
   "Our technique kills two birds with one stone," Lee said. "We're
   reducing the spatial resolution required to detect the molecule at the
   same time we're able to obtain chemical information about molecules
   while they are in a living cell. In a way, these gold particles are
   like 'nano-stars' because they illuminate the inner life of a cellular
   galaxy."
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   first time'

[25]Help hookup.com, an army of volunteers

   [26]The inspiration of Help Hookup is actually a comic book called
   Global Frequency by Warren Ellis. My brother, Alvin Wang, took the
   idea to startup weekend and they launched the idea this past weekend
   for hooking up volunteers. It is similar to the concepts of David
   Brin's "empowered citizens" and Glenn Reynolds "an army of Davids".
   Hooking up skilled volunteers with great causes and events.

     Global Frequency was a network of 1,001 people that handled the
     jobs that the governments did not have the will to handle. I
     thought that it was a great idea and it would be more powerful with
     1,000,001 people or 100,000,001 people. We would have to leave out
     the killing that was in the comic.
     Typhoons, earthquakes, and improperly funded education could all be
     handled. If there is a disaster, doctors could volunteer. Airlines
     could provide tickets. Corporations could provide supples. Trucking
     companies could provide transportation. Etc. State a need, meet the
     need. No overhead. No waste.

   [27]The main site is here it is a way for volunteers to hookup
   [28]The helphookup blog is tracking the progress.
   [29]The project has been covered on techcrunch.com
   [30]There is a facebook group
   [31]Track the online reaction via technorati
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[45]Interviewed by the speculist.com

   [46]I was interviewed for a podcast by the speculist.com website
   Some of things that I talked to them about was my view that many
   people are already making the choice to enhance some aspects of their
   body and mind using invasive and non-invasive approaches.
   Collective individual choices for future technology and the choices
   that are not commonly understood in the context of changing
   technology. We are choosing our future now.
   - 3 million in the USA choose steriods despite health downsides and
   access restrictions. 4 out of 5 for appearance reasons
   - 7 million worldwide use steroids
   - [47]11 million (in USA) choose cosmetic surgery despite results that
   are sub-optimal and risks to health
   - [48]dietary supplements are a $22+ billion industry
   - [49]Maybe 1 in 10 use drugs for better results on academic tests.
   It is not about "intelligence enhancement" it is about business
   productivity
   and academic performance.
   The drugs seem to help the performance of most students, but some do
   worse under its effect. Kids took practice tests with and without. If
   they thought it helped
   then they took it for the test
   [50]Some felt it gave them a 200 piont boost on SAT scores
   - non-invasive can work too (wikipedia, google etc...)
   - cheap mind machine interfaces for PS3, Xbox etc...
   these can mostly be grouped under crappy beta versions of human
   enhancement.
   Better versions of those kinds of enhancements are in the works:
   [51]Myostatin inhibitors are better and safer than steroids.
   Fake myostatin inhibitors are sold now.
   Millions will use it for muscle disease, to counter muscle wasting
   from old age and for performance and appearance enhancement.
   Apparently 4 times stronger effect than high dose steriods.
   Need to consume (eat more food) more - which is why evolution did not
   select those genese, but can help increase muscle for fat burning to
   counter obesity. So not only is it safer it could provide health
   benefits to the obese, elderly and those with muscle diseases. Since
   2005 there have been human trials.
   [52]Gene therapy -genetic engineering can provide more endurance,
   [53]radiation resistance, life extension.
   Unevenness of advancement- life extension
   There is already more than 30 year life expectency differences between
   [54]different groups in the USA and [55]around the world. There is
   0.1-0.3 years added to life expectancy every year.
   Many people do not want futurists to predict anything controversial or
   exceptional. Very rapid technological advancement, really powerful
   technology (AGI, versions of nanotech, certain space technologies,
   certain medical advancement etc...) While exceptional technology and
   breakthroughs are not what commonly occur every day, it is the
   exceptional breakthroughs that transform society over the longer term
   and we as a society need to lower the development barriers.
   Yes, certain choices and societal forces could cripple the development
   of those technologies. The Space program has not advanced because all
   the plans have not been focused on making big and meaningful things
   happen. Actual purpose political pork. My goal is to think of ways of
   getting around those blockages and to push for a better future and to
   spot movement around blockages that are already happening. Part of the
   reason is that I think the current societal choice/technology mix is
   not sustainable and people ignore the negatives of the current
   balance. 56 million dead/year is not something to be tolerated. People
   ignore the slaughter and the real dangers of the now. Nuclear power
   could kill 2000 people over 40 years when there is a really bad
   reactor design but that has to be compared to 1 million/year from coal
   and 3 million/year from air pollution.
   I think of the Tom Hanks character in Saving Private Ryan on the
   opening Omaha beach sequence. Some soldiers mistakenly believed it was
   better to hide behind the steel crosses on the beach or to not
   creatively attack the pill boxes that had them pinned down. I think of
   the difficult goals of getting space colonized in a major way or
   conquering diseases and making significant progress against age
   deterioration as pill boxes that have us pinned down on a dangerous
   beach. Just because the time has been stretched out to decades,
   centuries, millenia does not mean that we are not collectively on a
   dangerous beach. We can and should do a lot over the next 50 years and
   beyond. Every year 55 million people die from all the various causes
   and we are straining the ecosystem and facing growing dangers from the
   power of technology. Stepping back from where we are now to a
   "sustainable" position would be like retreating from the beack back
   into the sea. It is a bad plan because it would cost 5.5 billion lives
   and only save about 1 billion. Breakthrough out of being pinned down
   on the beach does not mean that everything is safe and utopia. There
   is still a struggle beyond with more risks and challenges. However,
   pressing forward in the most creative way with the best plans is the
   best course of action.
   In terms of a radically better future, why not choose the best plans
   we can come up with. Why stick to clearly failed or flawed plans just
   because that is what we have been doing ? If something is not working
   as well as it could then there should be change. The choice for the
   future does not have to be perfectly safe. It just has to be better
   overall than the current situation and path. We can and should do a
   lot better.
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[69]Progress on Stronger Carbon-Nanotube Fibers

   [70]Researchers have improved techniques for spinning fibers of carbon
   nanotubes: they make the nanotubes align in the fiber, creating fibers
   as strong as, or stronger than, materials such as Kevlar that are used
   in bullet-proof vests. Also, the nanotube fibers, unlike regular
   ropes, can be knotted without hurting their strength much.

     Alan Windle, a professor of materials science at the University of
     Cambridge, in England, made and tested the new nanotube fibers
     along with researchers at the Natick Soldier Research Development
     Center, in Massachusetts. Windle and his colleagues tugged on the
     nanotube fibers, finding that the weaker ones snapped at stresses
     around one gigapascal, making them comparable to steel, gram for
     gram.
     The better-performing carbon-nanotube fibers broke at around six
     gigapascals, beating the strengths that manufacturers report for
     materials used in bullet-proof vests, such as Kevlar. These
     nanotube fibers matched the highest reported strengths for a couple
     of the strongest commercially available fibers, Zylon and Dyneema,
     also used in bullet-proof vests. A lone, extremely strong nanotube
     fiber was off the charts, reaching nine gigapascals of stress--far
     beyond any other reported material--before breaking. Earlier work
     with carbon nanotubes has produced fibers that withstand at most
     three gigapascals.

   FURTHER READING
   [71]We are still waiting to hear if Superthread material is available.
   [72]New methods to make carbon nanotubes without metal catalysts could
   help prevent the defects that often cause nanotubes to break which are
   longer than one millimeter
   [73]Carbon nanotube production is increasing and prices are falling
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[87]Personal DNA services for about $1000

   [88]There are serveral new services, which will let customers analyze
   their DNA. This will tell them how likely it is that they will
   contract inherited diseases by creating a personalised, genetic
   profile.
   I think personalized medicine is the way to go. This is one piece of a
   larger puzzle. More analysis of this and other data is required. There
   needs to be individual computer models that represent our detailed
   physical condition. We need to be able to run simulations against that
   computer model to know what we should expect before we treat the
   physical person.

     23andMe, one of whose founders is married to the co-founder of
     Google, Sergey Brin, is one of a number of firms aiming to
     capitalise on their new market for personalised healthcare, where
     companies aim provide tailored, genetic information to customers.
     Customers will be able to take 'preventive action' in relation to
     their health.
     Last week, DeCode Genetics, an Icelandic firm, began a similar
     service for North American and European customers costing $985, and
     another Californian company, Navigenics, is also due to enter the
     market soon.
     Genetics experts criticised the service, saying that for the vast
     majority of customers it would be "scarcely of any use at all," and
     that 80 per cent of the information relevant to a determination
     about a customer's life expectancy, say, could be ascertained in a
     doctor's appointment.

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   [101]Rate 'Personal DNA services for about $1000'

More Recent Articles

     * [102]Printable carbon nanotube batteries
     * [103]New method to mnipulate light a million times more
       efficiently
     * [104]Nantero's newest NRAM promise is for 2008
     * [105]Silicon electronics can be printed by Ink Jet printers
     * [106]US 9th Appeals Court tosses federal fuel-economy standards

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  86. LYNXIMGMAP:file://localhost/tmp/mutt.html#outbrainMap_64651_3
  87. http://feeds.feedburner.com/~r/blogspot/advancednano/~3/187258205/personal-dna-services-for-about-1000.html
  88. http://technology.timesonline.co.uk/tol/news/tech_and_web/article2900692.ece
  89. http://feeds.feedburner.com/~f/blogspot/advancednano?a=ICXDlKB
  90. http://feeds.feedburner.com/~f/blogspot/advancednano?a=E1Xw7jB
  91. http://feeds.feedburner.com/~f/blogspot/advancednano?a=roFzmib
  92. http://feeds.feedburner.com/~f/blogspot/advancednano?a=91B4kXb
  93. http://feeds.feedburner.com/~f/blogspot/advancednano?a=S74Yq9b
  94. http://feeds.feedburner.com/~f/blogspot/advancednano?a=RULbmWB
  95. http://feeds.feedburner.com/~f/blogspot/advancednano?a=QU2VIbb
  96. http://feeds.feedburner.com/~f/blogspot/advancednano?a=1kNZdkB
  97. http://www.feedblitz.com/f/f.fbz?Fwd2FriendEdit=64651;297701;http://feeds.feedburner.com/~r/blogspot/advancednano/~3/187258205/personal-dna-services-for-about-1000.html;Personal%20DNA%20services%20for%20about%20$1000;103710
  98. http://www.feedblitz.com/f/f.fbz?Search=64651;297701;gene%20sequencing,future,medicine;Personal%20DNA%20services%20for%20about%20$1000;103710
  99. http://www.feedblitz.com/related.asp?http://feeds.feedburner.com/~r/blogspot/advancednano/~3/187258205/personal-dna-services-for-about-1000.html
 100. http://www.talkr.com/app/text_to_audio.app?feed_url=http%3a%2f%2ffeeds.feedburner.com%2fblogspot%2fadvancednano&permalink=http%3a%2f%2ffeeds.feedburner.com%2f~r%2fblogspot%2fadvancednano%2f~3%2f187258205%2fpersonal-dna-services-for-about-1000.html&src=5
 101. LYNXIMGMAP:file://localhost/tmp/mutt.html#outbrainMap_64651_4
 102. http://feeds.feedburner.com/~r/blogspot/advancednano/~3/186305941/printable-carbon-nanotube-batteries.html
 103. http://feeds.feedburner.com/~r/blogspot/advancednano/~3/185934094/new-method-to-mnipulate-light-million.html
 104. http://feeds.feedburner.com/~r/blogspot/advancednano/~3/185881003/nanteros-newest-nram-promise-is-for.html
 105. http://feeds.feedburner.com/~r/blogspot/advancednano/~3/185507592/silicon-electronics-can-be-printed-by.html
 106. http://feeds.feedburner.com/~r/blogspot/advancednano/~3/185433558/us-9th-appeals-court-tosses-federal.html
 107. http://tagline.feedblitz.com/nfc?affid=10059&sender=cf515ead64587146fb6815a2a013d226,feedblitz.com&rcpt=8da0e5c5ebdabb2bd85a8a5d3a603a7c,leitl.org&ranstr=d2464b11-9746-11dc-8854-0040ca82&group=64651
 108. http://www.feedblitz.com/adfaq.asp
 109. http://www.feedblitz.com/f/f.fbz?EmailRemove=_Mjk4NzI1M3w2NDY1MXxldWdlbkBsZWl0bC5vcmd8MTAzNzEw_
 110. http://www.feedblitz.com/f/f.fbz?Subscriptions=64651
 111. http://www.feedblitz.com/f
 112. http://www.feedblitz.com/f/f.fbz?EmailRemove=_Mjk4NzI1M3x8ZXVnZW5AbGVpdGwub3JnfDEwMzcxMA==_
 113. http://www.feedblitz.com/
 114. http://www.feedblitz.com/

----- End forwarded message -----
-- 
Eugen* Leitl <a href="http://leitl.org">leitl</a> http://leitl.org
______________________________________________________________
ICBM: 48.07100, 11.36820 http://www.ativel.com http://postbiota.org
8B29F6BE: 099D 78BA 2FD3 B014 B08A  7779 75B0 2443 8B29 F6BE

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