[tt] [GreyThumb] Fwd: [Bambct-list] Tufts BC seminar and CS Department Distinguished Lecture: Tuesday 11/6/2007 at 3pm: Sorin Istrail

Fri Nov 2 06:03:33 UTC 2007

----- Forwarded message from Adam Ierymenko <api at autoconstructive.com> -----

From: Adam Ierymenko <api at autoconstructive.com>
Date: Thu, 1 Nov 2007 17:26:59 -0400
To: Grey Thumb Boston <society at greythumb.org>
Subject: [GreyThumb] Fwd: [Bambct-list] Tufts BC seminar and CS Department Distinguished Lecture: Tuesday 11/6/2007 at 3pm: Sorin Istrail
X-Mailer: Apple Mail (2.752.3)

Thought some of you might be interested in attending this. If you  
are, let me know.

-Adam

Begin forwarded message:

>From: "Lenore Cowen" <cowen at cs.tufts.edu>
>Date: November 1, 2007 2:51:43 PM EDT
>To: bcb-seminar at cs.tufts.edu, bambct-list at molbio.mgh.harvard.edu,  
>csfacall at cs.tufts.edu
>Subject: [Bambct-list] Tufts BC seminar and CS Department  
>Distinguished Lecture: Tuesday 11/6/2007 at 3pm: Sorin Istrail
>
>
>Please join us for a special Bioinformatics and Computational
>Biology Seminar at Tufts on
>
>Tuesday, November 6th  from 3-4pm (NOTE UNUSUAL DATE AND TIME!)
>
>This seminar is sponsored by a special grant from the Tufts School of
>Engineering.
>
>Speaker: Sorin Istrail
>
>Affiliation: Brown University
>
>Title: ""The Regulatory Genome and the Computer"
>
>Abstract
>The definitive feature of the many thousand cis-regulatory control  
>modules in an animal genome is their information processing  
>capability. These modules are "wired" together in large networks  
>that control major processes such as development; they constitute  
>"genomic computers". Each control module receives multiple inputs  
>in the form of the incident transcription factors which bind to  
>them. The functions they execute upon these inputs can be reduced  
>to basic AND, OR and NOT logic functions, which are also the unit  
>logic functions of electronic computers. Here we consider the  
>operating principles of the genomic computer, the product of  
>evolution, in comparison to those of electronic computers. For  
>example, in the genomic computer intra-machine communication occurs  
>by means of diffusion (of transcription factors), while in  
>electronic computers it occurs by electron transit along pre- 
>organized wires. There follow fundamental differences in design  
>principle in respect to the meaning of time, speed, multiplicity of  
>processors, memory, robustness of computation and hardware and  
>software. The genomic computer controls spatial gene expression in  
>the development of the body plan, and its appearance in remote  
>evolutionary time must be considered to have been a founding  
>requirement for animal grade life.
>
>Speaker Bio:
>
>Sorin Istrail is the Julie Nguyen Brown Professor of Computational  
>and Mathematical Sciences, Professor of Computer Science, and  
>Director of the Center for Computational Molecular Biology at Brown  
>University. Dr. Istrail was previously Senior Director and then  
>Head of the Informatics Research Group of Celera Genomics, and as  
>such was instrumental in the company's human genome research. At  
>Celera, Dr. Istrail and his team developed powerful computational  
>tools for genome assembly comparison, automatic annotation of  
>genomes, computational analysis of SNPs, haplotype, and genome-wide  
>disease associations, DNA arrays analysis, and proteomics. Since  
>2003 Dr. Istrail has been a visiting associate in the Division of  
>Biology at California Institute of Technology, and an Adjunct  
>Professor of Biochemistry and Molecular Biology at George  
>Washington School of Medicine and Health Sciences. He was at Celera  
>Genomics and Applied Biosystems from April 2000 through February  
>2005. In 2003 he joined the ranks of Applied Biosystems Science  
>Fellows (one of the six Science Fellows in a company of 800  
>scientists). Prior to Celera, he founded and led the Computational  
>Biology Project at Sandia National Laboratories (1992-2000) within  
>the DOE Applied Mathematics Program, started at DOE by John von  
>Neumann. In 1998, his work on Protein Misfolding Simulations was  
>included by Scientific American in its "Best of 1998" list.
>
>In 2001, Dr. Istrail's work at Sandia on the statistical mechanics  
>of the Three-Dimensional Ising Model was ranked as the top 7th  
>achievement in Advanced Scientific Computing in the Top 100 U.S.  
>Department of Energy Most Important Discoveries in the DOE's first  
>25 years. From 1985 until 1992, Dr. Istrail was a visiting  
>scientist at Massachusetts Institute of Technology.
>
>Dr. Istrail's work has been focused on computational molecular  
>biology-- genomic regulatory systems and networks, genetic patterns  
>of inheritance of complex disease, protein folding and misfolding,  
>and comparative and integrative genomics. His research interests  
>also include combinatorial algorithms, mathematical logic,  
>computational complexity, and applications of computer science  
>methods to biology, physics, and chemistry. He is co-editor-in- 
>chief of the Journal of Computational Biology, co-founder of the  
>RECOMB Conference Series, co-editor of the MIT Press Computational  
>Molecular Biology book series, and co-editor of the Springer-Verlag  
>Lecture Notes in Bioinformatics book series.
>
>The talk is in Halligan 111
>
>
>You can see everything on our seminar website:
>
>http://bcb.cs.tufts.edu/bcb-seminar .html
>
>  including directions to campus and the room, speakers and titles,  
>and
>if you didn't do so already, instructions on how to join our
>electronic mailing list
>in order to get future announcements.  (please note; subscribing to
>the mailing list is a 2-step process: once you hit subscribe, you then
>have to  reply to the email you are sent to confirm you "really  
>want to
>subscribe" )
>
>
>Best, Lenore
>
>  ----------------------------
>   Lenore J. Cowen
>   Associate Professor
>   Dept. of Computer Science
>   Tufts University
>   http://www.cs.tufts.edu/~cowen/compbio
>    ----------------------------
>_______________________________________________
>Bambct-list mailing list
>Bambct-list at molbio.mgh.harvard.edu
>http://amber.mgh.harvard.edu/mailman/listinfo/bambct-list

-----------------------------------------------------------
This message was sent via the Grey Thumb Boston mailing
list.  Visit http://www.greythumb.org/list for more info.
-----------------------------------------------------------

----- End forwarded message -----
-- 
Eugen* Leitl <a href="http://leitl.org">leitl</a> http://leitl.org
______________________________________________________________
ICBM: 48.07100, 11.36820 http://www.ativel.com http://postbiota.org
8B29F6BE: 099D 78BA 2FD3 B014 B08A  7779 75B0 2443 8B29 F6BE